Ischemic stroke
Conditions
Interventions
Control Group:Basic pharmacotherapy + Sham acupuncture
Experimental Group:Basic pharmacotherapy + Jin's Three Needles
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria (1) Patients were subjected to the diagnostic criteria for ischemic stroke as defined in the *Chinese Stroke Prevention and Treatment Guidelines* (2021 edition), with confirmation by cranial CT or MRI. (2) Patients met the diagnostic criteria for stroke in traditional Chinese medicine. (3) The duration of cerebral infarction was =2 weeks after onset (following stabilization of vital signs) and less than 6 months, with patient age between 35 and 80 years. (4) The National Institutes of Health Stroke Scale (NIHSS) score was between 2 and 15, and there was no pre-existing physical disability related to this study prior to the current stroke onset. (5) Intracranial hemorrhage was excluded by cranial CT or MRI. (6) Patients were alert, with stable neurological status, and able to follow motor commands. (7) Written informed consent was obtained from the patient or their legal guardian.
Exclusion criteria
Exclusion criteria: Exclusion Criteria (1) Patients with limb motor dysfunction caused by other conditions, such as rheumatoid arthritis, claudication, etc.; (2) Patients with transient ischemic attack, subarachnoid hemorrhage, intracerebral hemorrhage, etc.; those who require arterial or venous thrombolysis or thrombectomy due to their condition; (3) Patients with acute or chronic infections, tumors, hematologic diseases, or other immune system–related disorders; severe organ dysfunction; (4) Patients with large-area cerebral infarction (neuroimaging indicates lesions involving =2 cerebral lobes or exceeding one-third of the middle cerebral artery territory) accompanied by mass effect, severe cerebral edema, or signs of cerebral herniation, or those requiring surgical treatment; (5) Patients who are pregnant, planning to become pregnant, or breastfeeding; (6) Patients currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Barthel Index, MBI;Modified Rankin Scale mRS;PAI-1;CD39;FMRI;ADP;tPA;D-Dimer;IL-6;TNF-a;VIP;SP; | — |
Countries
CHINA
Contacts
Public Contactjun He
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed