IgA Nephropathy
Conditions
Interventions
Exposed group:Yishen Qufeng Formule and Standard drug treatment
Non-exposed group:Standard drug treatment
Sponsors
Jiangsu Province Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Renal biopsy pathology diagnosed as IgA nephropathy; 2. 24-hour urinary protein quantity between 0.5–3.5 g/24h; 3. Estimated glomerular filtration rate =60 mL/min/1.73m²; 4. Age 18–80 years, any gender.
Exclusion criteria
Exclusion criteria: 1. Secondary IgA nephropathy, including IgA vasculitis nephritis, secondary IgA deposition caused by viral infections, inflammatory bowel disease, autoimmune diseases, liver cirrhosis, and post-infectious glomerulonephritis with predominant IgA deposition. 2. Renal biopsy pathology shows significant pathological activity, including crescentic glomerulonephritis, segmental sclerosis with podocyte lesions. 3. Currently receiving systemic corticosteroids, immunosuppressants, or biological agents. 4. Women who are breastfeeding or pregnant. 5. Patients with malignant tumors, severe cardiovascular disease, liver dysfunction, infections, or other diseases affecting the patient's quality of life. 6. Allergic to the traditional Chinese medicine formulation Yishen Qufeng Formule. 7. Deemed unsuitable for inclusion in the study by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Albumin-to-Creatinine Ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24-hour Urinary Total Protein;estimated Glomerular Filtration Rate;Urinary Red Blood Cell Count;Serum Creatinine;Serum Albumin;Cystatin C;Haemoglobin;Serum Uric Acid;EQ-5D-5L;Galactose deficient-IgA1; | — |
Countries
China
Contacts
Public ContactZhang Lu
Jiangsu Province Hospital of Chinese Medicine
Outcome results
None listed