Klebsiella pneumoniae pneumonia (KP pneumonia)
Conditions
Interventions
Experimental Group:The herbal formula Qiguiyin Decoction (composed of 60g of Astragalus membranaceus, 15g of Angelica sinensis, 15g of Honeysuckle, 10g of Artemisia annua, and 10g of Polygonum cuspida
Control Group:Symptomatic treatment
Sponsors
First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1) Meets the diagnostic criteria for KP pneumonia in both traditional Chinese medicine and Western medicine as outlined above; 2) Age =18 years old, gender; 3) Signed the informed consent form and agreed to participate in this clinical trial.
Exclusion criteria
Exclusion criteria: 1) Mechanically ventilated patients; 2) Patients with severe pneumonia, COVID-19, or other viral pneumonia; 3) Patients with a history of organ transplantation, cancer, chronic organ failure, autoimmune diseases, pulmonary fibrosis, or tuberculosis; 4) Patients with coagulation disorders or in end-stage or terminal states due to other severe illnesses; 5) Patients with contraindications or allergies to the drugs used in this study; 6) Patients with mental disorders who are unable to cooperate; 7) Pregnant or breastfeeding women; 8) Patients currently participating in or who have participated in other clinical trials within the past month; 9) Patients using similar traditional Chinese medicine (TCM) formulations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to recovery to pre-pneumonia condition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory Response Indicators;Pathogen clearance rate;Colony Forming Unit Change;The time required for fever reduction.;14-day clinical rate of severe cases;28-day mortality rate;Readmission rate within 60 days after discharge; | — |
Countries
China
Contacts
Public ContactSun Hongyuan
First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed