Chronic coronary syndromes
Conditions
Interventions
Treatment group:Conventional Western medical therapy combined with Shenzhu Guanxin Formula.
Control group:Conventional Western medical therapy for chronic coronary syndrome (CCS).
Sponsors
The Eighth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Patients who meet the CCS and traditional Chinese medicine syndrome diagnostic criteria specified in this study. 2) Aged 40–85 years, regardless of gender. 3) Voluntarily agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with severe hepatic or renal impairment (AST, ALT > 3 times the upper limit of normal, TBIL > 2 times the upper limit of normal, eGFR < 30 mL/min), malignant tumors, heart failure, or other severe diseases affecting survival. 2) Patients with psychiatric or neurological disorders who are unable to cooperate. 3) Women who are pregnant, planning to become pregnant, or breastfeeding. 4) Patients with allergies to the investigational drug or any of its components. 5) Patients who have participated in other drug trials within the past month. 6) Other patients whom the investigator considers unsuitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exercise tolerance-related parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Seattle Angina Questionnaire score;Inflammation-related markers;Platelet activation markers;Lipid- and glucose-related parameters;AI;Carotid and subclavian artery ultrasound examination;Electrocardiogram (ECG);Echocardiogram;New York Heart Association Functional Classification;Efficacy based on TCM syndrome scores; | — |
Countries
China
Contacts
Public ContactXu Danping
The Eighth Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed