LARS
Conditions
Interventions
TEAS group:Transcutaneous Electrical Acupoint Stimulation and postoperative management
Sham TEAS group:Sham Transcutaneous Electrical Acupoint Stimulation and postoperative management
Sponsors
Institute Of Basic Research In Clinical Medicine,China Academy Of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: a. Aged between 35 and 75 years; b. Cases undergoing radical resection or low anterior resection of rectal cancer with preservation of the anal sphincter, followed by stoma reversal; c. Karnofsky Performance Status (KPS) of =60, or Eastern Cooperative Oncology Group (ECOG) performance status of =2; d. No history of acupuncture or transcutaneous electrical acupoint stimulation (TEAS) within the past 3 months; e. Informed consent from the patient or their family.
Exclusion criteria
Exclusion criteria: a Patients with prior segmental colectomy or synchronous resection for double primary colorectal cancers, in addition to rectal resection; b Those with preoperative imaging or digital rectal examination suggesting anastomotic stricture, ulceration, or fistula; c Patients with a diagnosis of ulcerative colitis, Crohn's disease, or melanosis coli; d Individuals with significant comorbidities involving the heart, brain, lungs, liver, kidneys, or hematologic system, psychiatric disorders, or current use of glucocorticoids or immunosuppressive agents; e Patients with implanted cardiac pacemakers or other electronic implantable devices; f Patients with skin lesions, open wounds, or dermatological abnormalities at the acupoint sites; g Participants currently enrolled in another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of severe LARS in the two groups at 1, 2, and 3 months after stoma reversal;time to first flatus; | — |
Secondary
| Measure | Time frame |
|---|---|
| time to first feces;Severity of nausea, bloating, and pain;I-FEED Score;Wexner Score for Fecal Incontinence;patient reported bowel symptoms;Fecal Incontinence Quality of Life Questionnaire (FIQL);Use of analgesics; | — |
Countries
China
Contacts
Public ContactWang Mengqi
Institute Of Basic Research In Clinical Medicine,China Academy Of Chinese Medical Sciences
Outcome results
None listed