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Study on the effect of Sitting and lying "Liuzi jue" on diaphragmatic function in AECOPD patients post-extubation from invasive mechanical ventilation

Study on the effect of Sitting and lying "Liuzi jue" on diaphragmatic function in AECOPD patients post-extubation from invasive mechanical ventilation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001482
Enrollment
Unknown
Registered
2026-06-10
Start date
2025-11-01
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Interventions

experimental group:Conventional treatment and nursing care plus sitting and lying "Liuzi jue"

Sponsors

The Affiliated Hospital of Chengdu University of Traditional Chinese Medicinedicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Age 40~85 years; (2) Primary disease is AECOPD, and the patient meets the criteria for invasive mechanical ventilation due to AECOPD; (3) Duration of invasive mechanical ventilation = 48 hours, and the type of invasive mechanical ventilation is orotracheal intubation; (4) Extubation after passing a spontaneous breathing trial (SBT); (5) The patient is conscious and assessed as meeting the initiation criteria for sitting and lying "Liuzi jue" exercise; (6) Informed consent obtained from the patient and their family members. Patients must meet all the above criteria to be enrolled.

Exclusion criteria

Exclusion criteria: (1) Patients with unplanned extubation; (2) Patients with suspected or confirmed limb dysfunction or respiratory muscle weakness, such as myasthenia gravis, Parkinson's disease, spinal cord injury, etc.; (3) Patients with severe chronic organ dysfunction involving the liver, kidney, brain, etc., or those who have experienced acute cardiovascular events (e.g., myocardial infarction, aortic dissection, severe arrhythmias); (4) Patients with limited postural management who are unable to adopt a semi-recumbent or sitting position to perform sitting and lying "Liuzi jue" exercise; (5) Patients currently participating in other clinical intervention trials. Patients meeting any of the above criteria will be excluded.

Design outcomes

Primary

MeasureTime frame
Diaphragmatic Thickness Fraction;Diaphragmatic Excursion;

Secondary

MeasureTime frame
Diaphragmatic Thickness at the end of Inspiration;Diaphragmatic Thickness at the end of Expiration;Reintubation rate;ICU length of stay after extubation;Safety Assessment;

Countries

China

Contacts

Public ContactWangFang

The Affiliated Hospital of Chengdu University of Traditional Chinese Medicinedicine

ffdouble2025@163.com17396208963

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Jun 29, 2026