Mild Cognitive Impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnostic Criteria Refer to the diagnostic criteria for MCI in the 2018 edition of "Chinese Guidelines for the Diagnosis and Treatment of Dementia and Cognitive Disorders (Part 5): Diagnosis and Treatment of Mild Cognitive Impairment": (1) Cognitive impairment reported by the patient/informant or identified by the clinician. (2) Cognitive testing confirms impairment in one or more cognitive domains. (3) Mild impairment in instrumental activities of daily living, but still able to live independently. (4) Does not meet the criteria for dementia. 2. Inclusion Criteria (1) Meets the above diagnostic criteria; (2) Age range: 50-75 years old; (3) Patients who can understand the content of the scale and are willing to receive treatment; (4) Participants who are willing to provide informed consent for this study; (5) Have good compliance and are willing to suspend other treatments related to this disease during the treatment period. Those who meet the above criteria may be included in the study.
Exclusion criteria
Exclusion criteria: (1) Metabolic diseases, including anemia, thyroid dysfunction, and deficiencies in folate and vitamin B12, which may lead to cognitive decline; (2) Severe mental disorders, such as major depressive disorder, or a history of carbon monoxide poisoning; (3) Acute or severe life-threatening illnesses; (4) Severe visual, auditory, or language impairments that prevent completion of neuropsychological assessments; (5) Other conditions deemed inappropriate for participation in this study by the investigator. Patients meeting any of the above six criteria will be excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Auditory Word Learning Test - Huashan Edition;Shape Connecting Lines Test;Boston Naming Test;Hamilton Depression Rating Scale;Hamilton Anxiety Rating Scale;Pittsburgh Sleep Quality Index (PSQI);The concentration of oxyhemoglobin in the frontal lobe of the brain; | — |
Countries
China
Contacts
Shuguang Hospital Affiliated to Shanghai University of TCM