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Development of a clinical prediction model for in-hospital mortality due to heart failure combining traditional Chinese and Western medicine

Development of a clinical prediction model for in-hospital mortality due to heart failure combining traditional Chinese and Western medicine

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2026001359
Enrollment
Unknown
Registered
2026-05-26
Start date
2022-05-14
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure

Interventions

Observation Group A (patients who did not die during hospitalization):No intervention measures
Group B (In-hospital deceased patients):None

Sponsors

Department of Cardiology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: (1)The discharge date is from January 1, 2019 to December 31, 2021. (2) For patients whose discharge diagnosis on the first page of the medical record includes heart failure (such as left heart failure, total heart failure, right heart failure, acute heart failure, chronic heart failure, etc.), the medical record is identified through the codes in the 10th Edition of the International Classification and Coding System of Diseases. The ICD-10 codes related to heart failure include I50.001, I50.901, I50.904, I50.006, I50.102, I50.915, I50.914, I50.916, I50.918, I50.905, I50.103, I50.917, I50.003). I50.919, I50.004, I50.005, I50.106, I50.107, I50.911. (3) The medical records are relatively complete and the data is true. (4) The diagnostic criteria for heart failure are based on the 2018 edition of the "Chinese Guidelines for the Diagnosis and Treatment of Heart Failure" : 1) Heart failure with reduced ejection fraction: Symptoms and/or signs of heart failure, LVEF35pg/ml, or NT-proBNP>125ng/ml), simultaneously meeting at least one of the following conditions: left ventricular hypertrophy and/or left atrial enlargement, abnormal cardiac diastolic function; 3) Heart failure with preserved ejection fraction: Symptoms and/or signs of heart failure, LVEF=50%, elevated natriuretic peptide (BNP>35pg/ml, or NT-proBNP>125ng/ml), simultaneously meeting at least one of the following conditions: left ventricular hypertrophy and/or left atrial enlargement, abnormal cardiac diastolic function.

Exclusion criteria

Exclusion criteria: (1) Patients with unclear outcomes; (2) Patients under the age of 18; (3) Patients who do not meet the diagnostic criteria of the 2018 edition of the "Chinese Guidelines for the Diagnosis and Treatment of Heart Failure"; (4) Patients with blood diseases, leukemia or mental disorders

Design outcomes

Primary

MeasureTime frame
The outcome (life or death) of the patient at discharge;weight;age;date of birth ;Gender;ethnic group;past medical history;Personal history (Smoking history);heart rate;blood pressure;Is the cause of heart failure myocardial ischemia?;The duration of heart failure;Is heart failure the main cause of hospitalization?;left ventricular ejection fraction;Left ventricular end-diastolic diameter; left ventricular diastolic function;NYHA classification;Symptoms (whether breathing is difficult, whether fatigue, etc.);Signs (moist rales in the lungs, edema in the lower extremities, etc.);Medications taken before admission;Medications taken during hospitalization; blood routine examination (including white blood cell count, neutrophil count, lymphocyte count, monocyte count, neutrophil percentage, monocyte percentage, hemoglobin, hematocrit, platelet count, etc.);Liver function (albumin, alanine aminotransferase, aspartate aminotransferase, total bilirubin, etc.);Renal function (including creatinine, urea nitrogen, and glomerular filtration rate);troponin;NT-proBNP or BNP;Electrolytes (including potassium ions, sodium ions, chloride ions, bicarbonate ions, etc.);Traditional Chinese Medicine diagnosis (including disease names and syndrome types);The solar term on the day of admission;tongue characteristics;pulse characteristics;Whether traditional Chinese medicine decoctions were used during hospitalization;

Countries

China

Contacts

Public ContactYi Yang

Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

851290967@qq.com86-18102459958

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Jun 11, 2026