Stimulant (including amphetamine, methamphetamine, or methcathinone) dependence, in sustained partial remission
Conditions
Interventions
Sham Acupoint Cagut Embedding Group:Sham Acupoint Cagut EmbeddingSham Acupoint Cagut Embedding
Sponsors
The Second Affiliated Hospital of Yunnan University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 53 Years
Inclusion criteria
Inclusion criteria: Meets the diagnostic criteria for methamphetamine (METH) dependence, with a history of METH abuse of = 6 months. In the protracted withdrawal phase (cessation = 2 weeks), with a withdrawal duration of = 1 month and negative urine drug screen. Meets the Rome IV criteria for functional constipation, with symptoms persisting for = 1 month. Aged 18–52 years, alert and oriented, with stable vital signs, able to cooperate with treatment and examinations. No use of laxatives, antidepressants, or other medications affecting intestinal and central nervous system function in the past month. Voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: Patients with severe cardiac, hepatic, renal, hematological diseases, severe mental disorders or infectious diseases. Patients with organic digestive diseases, skin infections, coagulation disorders or other contraindications for catgut embedding therapy. Patients with a history of impulsive or violent behavior, suicide attempts, epilepsy or organic brain diseases. Patients currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation symptom score;Drug craving score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gut Microbiota Detection;Functional Near-Infrared Spectroscopy (fNIRS) Detection; | — |
Countries
China
Contacts
Public ContactLei Pan
Rehabilitation Medicine Department, Second Affiliated Hospital of Yunnan University of Chinese Medicine
Outcome results
None listed