osteoarthritis
Conditions
Interventions
The herbal intervention group for the kidney deficiency syndrome in KOA:There were 49 patients each with kidney yin deficiency, kidney yang deficiency, and kidney yin-yang deficiency. On the basis of
KOA Kidney Deficiency Syndrome Conventional Treatment Group:On the basis of oral administration of hydrochloric acid chondroitin, a placebo was given.
Sponsors
No. 613, Huangpu Avenue West, Tianhe District, Guangzhou City, Guangdong Province. The First Affiliated Hospital of Jinan University
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age: 60 - 75 years old, gender not restricted. 2) Diagnosed with OA based on X-ray/MRI/clinical symptoms. 3) Kellgren & Lawrence grade between 0 and II. 4) Meets the diagnostic criteria of kidney deficiency syndrome (kidney yin deficiency, kidney yang deficiency, or both kidney yin and yang deficiency) in traditional Chinese medicine. 5) Agrees to participate in this study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Secondary arthritis: Rheumatoid arthritis, ankylosing spondylitis, gouty arthritis, infectious arthritis, traumatic arthritis, etc. 2) Severe joint structural abnormalities: Deformed, disabled, or dysfunctional knee joints. 3) Complicated with systemic diseases: Severe heart, liver, or kidney failure, malignant tumors, blood system diseases, immune deficiencies, tuberculosis, hemophilia, mental disorders, etc. 4) Received joint cavity injections (such as hormones, hyaluronic acid) within the past month, or have been taking long-term hormones or immunosuppressants. 5) Women who may be pregnant or planning to get pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kidney Deficiency Score and Therapeutic Effect Evaluation Scale;WOMAC Score Scale;HSS Rating Scale;Degree of swelling in the knee joint;VAS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurement of X-ray joint space width and bone spurs;MRI MOAKS Rating Scale; | — |
Countries
China
Contacts
Public ContactHuantian Zhang
The First Affiliated Hospital of Jinan University
Outcome results
None listed