Dissociative Identity Disorder
Conditions
Interventions
Acupuncture group:Duloxetine routine treatment in combination with acupuncture therapy.
Sham group:Duloxetine standard treatment plus sham needle treatment.
Sponsors
Beijing Anding Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Inclusion criteria for DPRD participants: 1) Participants must be clinically diagnosed with depersonalization-derealization disorder according to DSM-5 criteria by two attending physicians or above, and also meet the diagnostic criteria for liver and kidney yin deficiency. 2) Total score on the Cambridge Depersonalization Scale (CDS) must be greater than 70. 3) Age between 18-45 years old. 4) Right-handed. 5) Educational level of junior high school or above. 6) No skin damage or abscess at acupuncture sites. 7) Able to understand and complete the requirements of this experiment, and willing to sign the informed consent form. Participants must meet all seven criteria to be eligible for inclusion. (2) Inclusion criteria for healthy controls: 1) Screened using the MINI interview, participants must not meet the diagnostic criteria for any mental disorder according to DSM-5. 2) No family history of mental illness. 3) Age between 18-45 years old. 4) Right-handed. 5) Educational level of junior high school or above. 6) Able to understand and complete the requirements of this experiment, and willing to sign the informed consent form. Healthy controls who underwent MRI scans prior to the start of the study will also be included in the analysis after re-obtaining informed consent
Exclusion criteria
Exclusion criteria: (1) Individuals with severe suicidal tendencies; (2) Known alcohol abusers or individuals with substance dependence; (3) Individuals with severe or unstable medical conditions such as heart, liver, kidney, endocrine, or hematological diseases; (4) Individuals with organic brain damage; (5) Individuals diagnosed with severe mental disorders. Any individual meeting any of the above criteria should be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CDS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Scale (Hamilton Rating Scale for Anxiety, HAMA);Nuclear Magnetic;Hamilton Depression Rating Scale (HAMD);Self-Rating Anxiety Scale (Zung's Self-Rating Anxiety Scale, SAS);Subliminal Self-Face Recognition Task;Depression Self-Rating Scale (Zung's Self-rating Depression Scale, SDS);General Functioning Scale (Global Assessment of Functioning, GAF);Dissociative Disorder Chinese Medicine Syndrome Type Observation Form; | — |
Countries
China
Contacts
Public ContactSisi Zheng
Beijing Anding Hospital Affiliated to Capital Medical University
Outcome results
None listed