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Clinical study on the treatment of postmenopausal osteoporosis with Weishen Decoction by regulating osteogenic differentiation of BMSCs through miRNA/Wnt

Clinical study on the treatment of postmenopausal osteoporosis with Weishen Decoction by regulating osteogenic differentiation of BMSCs through miRNA/Wnt

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001288
Enrollment
Unknown
Registered
2026-05-26
Start date
2024-05-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postmenopausal osteoporosis

Interventions

Traditional Chinese Medicine Treatment Group:traditional Chinese medicine+basic treatment
Placebo control group:placebo+basic treatment

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Simultaneously meeting the diagnostic standards of Western medicine and traditional Chinese medicine syndrome diagnosis; 2.Have normal communication skills and sign informed consent forms; 3.Postmenopausal women.

Exclusion criteria

Exclusion criteria: 1.Patients with secondary osteoporosis; 2.Traditional Chinese medicine diagnosis has obvious mixed syndrome; 3.Those who suffer from severe cardiovascular and cerebrovascular diseases respiratory system diseases etc. and have an impact on syndrome differentiation; 4.The use of other disease treatment drugs affects the determination of experimental indicator

Design outcomes

Primary

MeasureTime frame
Bone Mineral Density;Traditional Chinese Medicine Syndrome Score;

Secondary

MeasureTime frame
Procollagen Type I N-Terminal Propeptide;Bone-Specific Alkaline Phosphatase;ß-catenin;Dickkopf-related protein 1;Bone Gla Protein;

Countries

China

Contacts

Public ContactZhang Peng

Xuzhou Central Hospital

lsfzywww@qq.com18952171694

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Jun 11, 2026