Obese type 2 diabetes mellitus
Conditions
Interventions
Tuina group:Basic treatment + Metformin+ Abdominal Tuina manipulation
Control group:Basic treatment + Metformin+ Non-meridian non-acupoint pressure
Sponsors
Dongfang Hospital of Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria for type 2 diabetes mellitus (T2DM); 2) Glycated Hemoglobin < 9%; 3) Meet the diagnostic criteria for obesity; 4) Aged 18–80 years, with no gender restriction; 5) No contraindications to metformin use (e.g., eGFR = 60 mL/min, absence of severe gastrointestinal diseases); 6) Voluntarily sign the informed consent form, cooperate with sample collection and indicator testing, comply with follow-up requirements, and have no clear plan to withdraw from the study prematurely.
Exclusion criteria
Exclusion criteria: 1) Type 1 diabetes mellitus or specific types of diabetes; 2) Complicated with severe heart, liver, or kidney diseases (NYHA cardiac function class = III, decompensated liver cirrhosis, eGFR < 30 mL/min); 3) Abdominal skin lesions, tumors, or acute abdomen; 4) Pregnant or breastfeeding women; 5) Participation in other clinical trials within the past month; 6) Mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting Plasma Glucose;2-hour Postload Plasma Glucose;Glycated Hemoglobin;Fasting Insulin;Homeostasis Model Assessment of Insulin Resistance;Weight;Body Mass Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Waist-to-Hip Ratio; Blood Flow Restriction;Total Cholesterol;Triglyceride;Low-Density Lipoprotein Cholesterol;High-Density Lipoprotein Cholesterol;Traditional Chinese Medicine (TCM) symptom score;Diabetes Mellitus Quality of Life Scale; | — |
Countries
China
Contacts
Public ContactGuo Sheng
Dongfang Hospital of Beijing University of Chinese Medicine
Outcome results
None listed