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Clinical Observation of Electroacupuncture at He-Mu Acupoints the Efficacy in Septicemia with Gastrointestinal Dysfunction and Its Regulatory Effect on Gut Microbiota

Clinical Observation of Electroacupuncture at He-Mu Acupoints the Efficacy in Septicemia with Gastrointestinal Dysfunction and Its Regulatory Effect on Gut Microbiota

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2026001264
Enrollment
Unknown
Registered
2026-05-18
Start date
2026-05-20
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septicemia with Gastrointestinal Dysfunction

Interventions

Control group:Conventional Western medical treatment plan
electroacupuncture at He-Mu points group:Based on the conventional treatment of the control group, electroacupuncture was applied using combined acupoints. Acupoint prescription: Tianshu, Shangjuxu
Zhongwan, Zusanli
Guanyuan, Xiajuxu Procedure: The patient was placed in a supine position. Acupoints were located according to the 'National Standard of the People's Republic of China - Locations of Acupoints' (GB1234
Shangjuxu, Zusanli, and Xiajuxu 1.0–2.0 cun. Strict sterile procedures were followed throughout the needling. Needles were retained for 30 minutes each session, once daily, for 7 consecutive days.

Sponsors

The Affiliated Guangzhou Hospital of TCM of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Meets the diagnostic criteria for sepsis-associated acute lung injury (ALI) according to the 2020 'Expert Consensus on the Integrated Chinese and Western Medicine Diagnosis and Treatment of Sepsis-Induced Lung Injury'; this study will apply for approval from the Ethics Committee of the Affiliated Traditional Chinese Medicine Hospital of Guangzhou Medical University, and all enrolled patients will obtain informed consent from themselves or their families and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Individuals with severe combined liver and kidney dysfunction, blood disorders, endocrine, immune, or other underlying diseases; 2) Those with trauma, tuberculosis, or malignant tumors; 3) Patients who have undergone gastrointestinal surgery or have organic gastrointestinal diseases; 4) Individuals with mental disorders, lacking self-control, or unable to express themselves clearly; 5) Those who do not accept acupuncture therapy, have poor compliance, or do not actively cooperate with treatment; 6) Pregnant women; 7) Individuals under 18 or over 80 years old.

Design outcomes

Primary

MeasureTime frame
White blood cell count;Neutrophil percentage;Procalcitonin;C-reactive protein;Interleukin-6;Serum amyloid protein A;16S rDNA high-throughput sequencing;

Secondary

MeasureTime frame
Gastric residual volume;bowel sound frequency;weekly bowel movement frequency;Bristol score;

Countries

China

Contacts

Public ContactMoyuxiao

The Affiliated Guangzhou Hospital of TCM of Guangzhou University of Chinese Medicine

529499369@qq.com18826404702

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Jun 11, 2026