Liver abscess
Conditions
Interventions
Xianfang Huoming Yin Treatment Group:Xianfang Huoming Yin combined with ß-lactam antibiotics and percutaneous catheter drainage.
Standardized Treatment Control Group:ß-lactam antibiotics + needle catheter drainage
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Adult patients aged between 18 and 80 years; patients presenting with characteristic clinical manifestations of liver abscess, such as chills, high fever, liver region pain, fatigue, loss of appetite, etc.; imaging examinations (ultrasound (US), computed tomography (CT), or magnetic resonance imaging (MRI)) showing characteristic features of liver abscess; pus extraction via aspiration or surgery, confirmed by bacterial culture results; exclusion of amebic liver abscess, tuberculous liver abscess, and liver abscess after liver transplantation; willingness to participate in the study with informed consent. The process of obtaining informed consent should comply with Good Clinical Practice (GCP) regulations.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1) Liver abscesses caused by amebic, tuberculosis, fungi, or other microorganisms, as well as liver abscesses caused by trauma; 2) Age 80 years; 3) Pregnancy or breastfeeding; 4) History of allergy to pus-scattering agents; 5) Unable to obtain informed consent or patients who do not agree; 6) Patients who are not actively participating in comprehensive and aggressive treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time for the abscess cavity to reduce by 30% or achieve complete absorption.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of fever subsiding;Time of relief from abdominal pain;Procalcitonin;C-reactive protein;The normal time of inflammatory factors.;Pus bacterial culture;Stool bacterial culture; | — |
Countries
China
Contacts
Public ContactLi Jiabin
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed