Precancerous lesion of gastric cancer
Conditions
Interventions
Lesion group:Not applicable
Sponsors
Shenzhen Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Participants aged 18 years or older were all subjected to gastroscopy. Based on endoscopic and pathological examinations, they were diagnosed as having normal gastroscopy (control group) or atrophic gastritis combined with intestinal metaplasia (lesion group). 2) They voluntarily participated in the study and signed the informed consent form. 3) Diagnostic criteria: The control group consisted of those who were diagnosed with chronic superficial gastritis or no obvious lesions through endoscopic examination. The lesion group included those who had gastric mucosal lesions detected by endoscopy and underwent gastric mucosal biopsy, and whose pathological diagnosis was precancerous lesions (the focus of this study was on atrophy combined with intestinal metaplasia). The pathological diagnosis was independently reviewed by two pathologists, and in case of inconsistent diagnoses, a third pathologist made the final determination. The pathologists were unaware of the diagnosis results and serum test results of the study participants during the diagnosis process.
Exclusion criteria
Exclusion criteria: 1) Patients with confirmed gastric cancer; 2) Those whose tongue lesions affect the collection of tongue images; 3) Patients with severe liver or kidney dysfunction; 4) Those who have recently taken drugs that affect gastric function (such as proton pump inhibitors, antibiotics, etc.); 5) Patients with severe systemic diseases or acute or chronic infections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The model's discrimination ability ;The model's classification performance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical consistency evaluation of the constructed model;Clalibration degree and calibration curve of the constructed model;the results of difference analysis of the constructed model; | — |
Countries
China
Contacts
Public ContactJing-wei Li
Shenzhen Traditional Chinese Medicine Hospital
Outcome results
None listed