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A randomized controlled trial of seed-sized moxa cone moxibustion for cancer-related fatigue in patients with stage III-IV non-small cell lung cancer undergoing chemotherapy

A randomized controlled trial of seed-sized moxa cone moxibustion for cancer-related fatigue in patients with stage III-IV non-small cell lung cancer undergoing chemotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001216
Enrollment
Unknown
Registered
2026-05-14
Start date
2026-05-31
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Moxibustion with Moxa Cones Group:Moxibustion with Moxa Cones
Sham moxibustion group:Grain-sized moxibustion therapeutic apparatus

Sponsors

Shanxi University of Traditional Chinese Medicine Affiliated Acupuncture and Massage Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 (inclusive); 2. Patients with pathologically diagnosed non-small cell lung cancer, who are in stages III-IV according to TNM staging, are scheduled to undergo chemotherapy; they are planned to receive at least two cycles of standardized chemotherapy regimen; 3. Meet the diagnostic criteria of CRF; 4. Karnofsky functional status score = 60; 5. Patients who receive standard chemotherapy regimens: TP regimen (paclitaxel + cisplatin/carboplatin) or DP regimen (docetaxel + cisplatin/carboplatin) chemotherapy, with the chemotherapy regimen in accordance with the recommended dosage and cycle as per the 2025 CSCO Guidelines for the Diagnosis and Treatment of Primary Non-Small Cell Lung Cancer; 6. Those with an expected survival period of more than 3 months; 7. Voluntarily sign the informed consent form and be willing to cooperate in completing the study.

Exclusion criteria

Exclusion criteria: 1. Those with damaged, infected, or allergic skin at the acupoints where wheat grain moxibustion is applied; 2. Patients with combined severe dysfunction of vital organs such as the heart, liver, and kidneys; 3. Patients with mental illness who are unable to cooperate; 4. Those who are currently participating in other clinical trials that may affect immune function; 5. Pregnant or lactating women; 6. Individuals with an allergy to tobacco smoke.

Design outcomes

Primary

MeasureTime frame
Cancer-related fatigue severity scoring;

Secondary

MeasureTime frame
Physical Condition Rating;Quality of Life;Anxiety and depressive mood;Insomnia severity;Predefined Cycle Chemotherapy Completion Rate;

Countries

China

Contacts

Public ContactZhang Tiansheng

Shanxi University of Traditional Chinese Medicine Affiliated Acupuncture Hospital

zts910@163.com+86 134 6683 8493

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Jun 11, 2026