Major depressive disorder
Conditions
Interventions
Acupuncture group:Electroacupuncture Needle Stimulation at Acupoints Prescription
Sham acupuncture group:Acupuncture at non-meridian, non-acupoint sites, the electroacupuncture device does not output current.
Sponsors
Tsinghua University Yuquan Hospital (Tsinghua University Hospital of Integrated Traditional Chinese and Western Medicine)
Eligibility
Sex/Gender
All
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 59 years, and right-handed; 2.Patients who have received systematic antidepressant treatment (including antidepressant medications, sedative-hypnotics, electroconvulsive therapy, or transcranial magnetic stimulation) within the 4 weeks prior to enrollment; 3.Having a total score on the 17-item Hamilton Depression Rating Scale (HAMD-17) greater than 7 and less than or equal to 24; 4.Voluntary participation in the study, with written informed consent provided by the patient themselves or their legally authorized guardian.
Exclusion criteria
Exclusion criteria: 1.Diagnosis of other major psychiatric disorders or presence of psychotic symptoms. 2.History of other severe somatic diseases (e.g., cardiovascular/cerebrovascular diseases, autoimmune diseases), or current/past neurological or organic brain diseases. 3.Current or past history of alcohol dependence or abuse of other psychoactive substances. 4.Women who are lactating, pregnant, or menstruating. 5.Patients who have participated in other clinical drug trials within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montgomery-Åsberg Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale;Positive and Negative Affect Schedule;Maudsley Three-Item Visual Analogue Scale; | — |
Countries
China
Contacts
Public ContactFan Chunling
Tsinghua University Yuquan Hospital (Tsinghua University Hospital of Integrated Traditional Chinese and Western Medicine)
Outcome results
None listed