Chemotherapy-induced nausea and vomiting (CINV)
Conditions
Interventions
Standard treatment group:Ondansetron Injection 8mg + 0.9% Sodium Chloride Injection 20ml, intravenous injection
Burying thread + Standard treatment group:Add "Sanwan point" implantation therapy on the basis of standard treatment. The standard treatment protocol remains the same as before.
Sham implantation + Standard treatment group:In addition to the standard treatment, a sham acupuncture procedure was added at the Sanwan acupoint. The standard treatment protocol remains the same as b
Sponsors
Shaanxi Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 76 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet diagnostic criteria, have indications for chemotherapy without contraindications, require chemotherapy, or require adjuvant chemotherapy after surgery; 2. Age between 18 and 76 years; 3. Functional status score (Karnofsky Performance Status, KPS) >70 points; 4. Expected survival >3 months; 5. No nausea or vomiting symptoms and no use of antiemetic drugs within 24 hours prior to chemotherapy; 6. No symptoms of gastrointestinal obstruction; 7. Voluntary participation in this treatment plan and signed informed consent.
Exclusion criteria
Exclusion criteria: 1)Patients with brain metastasis from malignant tumors, increased intracranial pressure, gastrointestinal obstruction, brain tumors, cerebrovascular diseases, or other causes of refractory vomiting; 2) Patients with coagulation dysfunction, thrombocytopenia, or bleeding disorders; 3) Patients who have interrupted chemotherapy for other reasons; 4) Patients with severe skin damage or a history of protein allergy; 5) Patients with a history of needle syncope; 6) Late-stage critically ill patients; 7) Pregnant women, breastfeeding women, individuals with mental illness, or severe heart disease patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| National Cancer Institute Common Terminology Criteria for Adverse Events Version 5.0; | — |
Secondary
| Measure | Time frame |
|---|---|
| Karnofsky Performance Status (KPS);Brief Fatigue Scale;Adverse Reaction Record; | — |
Countries
China
Contacts
Public ContactHou Jun
Shaanxi Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed