Metabolic dysfunction-associated fatty liver disease
Conditions
Interventions
Training cohort:Retrospective observational study with no intervention
validation cohort:Retrospective observational study with no intervention
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 98 Years
Inclusion criteria
Inclusion criteria: 1.Adult subjects aged = 18 years; 2.Subjects who underwent MRI-PDFF examination and obtained liver fat content measurement results at our center during the study period; 3.Subjects who completed blood biochemical tests within 3 months; 4.Subjects who completed body composition assessment or anthropometric measurements (e.g., BMI, body fat percentage, visceral fat, etc.) within 3 months; 5.Subjects with complete clinical data and laboratory data.
Exclusion criteria
Exclusion criteria: 1.Significant alcohol consumption: >40 g/day for men and >20 g/day for women; 2.Other definite liver diseases, including but not limited to: 3.Viral hepatitis (HBV, HCV, etc.); 4.Autoimmune liver disease; 5.Drug-induced liver injury (DILI); 6.Inherited metabolic liver diseases (e.g., Wilson's disease); 7.Previously diagnosed liver cirrhosis, hepatocellular carcinoma (HCC), or severe structural liver abnormalities; 8.Pregnant or lactating women; 9.Recent use of medications that may significantly affect hepatic steatosis (e.g., long-term glucocorticoids); 10.Subjects with missing clinical data or key indicators; 11.Poor-quality MRI images or those with unreliable PDFF measurement results.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Hepatic and renal function;Fasting blood glucose;Blood lipids;Blood routine test;Weight;Body Mass Index (BMI);Fat mass;Body fat percentage; | — |
Countries
China
Contacts
Public ContactLingying Huang
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed