allergic rhinitis
Conditions
Interventions
Nasal acupuncture group:Nasal acupuncture treatment
medication group:Oral loratadine tablets
Acupuncture and Medicine Combination Group:Nasal acupuncture combined with oral loratadine tablets
Sponsors
Hangzhou Red Cross Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Those who meet the Western diagnostic criteria for allergic rhinitis; (2) Age between 18 and 65 years old; (3) The patient signs informed consent, voluntarily participates in the trial, and cooperates to complete the follow-up.
Exclusion criteria
Exclusion criteria: (1) Patients with upper respiratory tract infections, drug-induced rhinitis, asthma and other diseases; (2) Combining asthma and acute exacerbation of cardiovascular and cerebrovascular diseases, immunodeficiency diseases, head and facial trauma, tumors, and organ transplant surgery; (3) Pregnant or lactating women; (4) Patients who are currently using other medications to treat this disease; (5) Patients with dizziness and those who are known or suspected to be allergic to the study drug; (6) Patients who have participated or are currently participating in other clinical observation projects for new drugs within the previous month of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Symptom Score of Rhinitis (TNSS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Nasal Symptom Scale (TNNSS);Quality of Life Questionnaire for Rhinoconjunctivitis in General Activities (RQLQ);Nasal signs score; Serum levels of interleukin-2 (IL-2), IL-4, IL-6, IL-10, IL-17, interferon gamma (IFN - ?), and tumor necrosis factor alpha (TNF - a);Th17 and Treg levels in serum;ROR ? t and Foxp3 mRNA in nasal mucosa; | — |
Countries
China
Contacts
Public ContactLiu Jin
Hangzhou Red Cross Hospital
Outcome results
None listed