Chronic Obstructive Pulmonary Disease (COPD)
Conditions
Interventions
Ususal Care:Usual care for COPD
ePRO-Guided Acupuncture :Usual care for COPD+ePRO-Guided Acupuncture
Sponsors
Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 40–80 years; 2. Patients with Stage II, III, or IV COPD based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria and with a forced expiratory volume in one second (FEV1) between 25% and 80% of the predicted value; 3. No acute exacerbation and no sign of edema within 4 weeks prior to enrollment; 4. Receiving stable treatment according to GOLD recommendations for at least 3 months prior to enrollment, with no changes in the treatment regimen. 5. Able to walk independently and perform activities of daily living; 6. At least one hospital visit or consultation at a respiratory clinic for COPD within the past 12 months; 7. Informed consent obtained from patients or their legal representatives.
Exclusion criteria
Exclusion criteria: 1) Patients with language, memory, cognitive or psychiatric disorders, or with limited education that may prevent them from understanding them questionnaires or operating electronic tools; 2) Patient with following comorbidities: chronic heart failure, autoimmune diseases, chronic renal failure, chronic hepatic failure, or malignant tumors. 3) Patients with the following respiratory diseases: active pulmonary tuberculosis, bronchial asthma, severe bronchiectasis, or interstitial lung disease; 4) History of lung surgery for COPD, including segmentectomy, wedge resection, lobectomy, pneumonectomy, or lung volume reduction surgery (including bronchoscopic lung volume reduction); 5) Patients requiring long-term oxygen therapy (LTOT) (oxygen therapy >15 hours/day). 6) Current participation of another clinical trials or has participated in other clinical trials within 90 days preceding trial inclusion; 7) History of any acupuncture treatment in the prior 1 month; 8) Unable to administer acupuncture due to local skin infection at or near the acupoints, limb defects, or other conditions; 9) Women who are pregnant or in lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time from randomization to first COPD-related hospitalization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Annual COPD-related hospitalization/ER visits;Annual self-reported COPD exacerbations;COPD-related mortality within 1 year;All-cause mortality within 1 year;SGRQ score change from baseline to 12 months;FEV1% predicted change from baseline to 12 months;the Borg scale score after the 6-minute walk test from baseline to 12 months; | — |
Countries
China
Contacts
Public ContactWang Yuting
Chengdu University of Traditional Chinese Medicine
Outcome results
None listed