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Clinical Efficacy and Mechanism Study of Ziqingmanxin Dan in Treating Ventricular Premature Contractions

Clinical Efficacy and Mechanism Study of Ziqingmanxin Dan in Treating Ventricular Premature Contractions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001107
Enrollment
Unknown
Registered
2026-04-28
Start date
2025-02-18
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventricular Premature Contractions

Interventions

treatment group:Treat with the oral Ziqingmanxin Dan.
control group:Administer metoprolol succinate sustained-release tablets (Betaloc). The initial dose is 23.75 mg, taken orally once daily. The dosage should be adjusted according to the patient's heart

Sponsors

Wuxi Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Meets the diagnostic criteria for ventricular premature contractions in Western medicine. (2) Meets the diagnostic criteria for the syndrome of palpitations and deficiency of both qi and yin in traditional Chinese medicine. (3) Age over 18 years old. (4) No contraindications to treatment. (5) Agree to receive traditional Chinese medicine treatment orally. (6) The subjects have given informed consent and voluntarily signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) There are patients with severe critical cardiovascular emergencies such as decompensated heart failure; (2) There are patients with severe peripheral vascular diseases at risk of gangrene; (3) There are patients with severe arrhythmias, and those with clear indications for electrical cardioversion or non-drug treatment; (4) There are patients with severe liver, kidney or malignant tumors and other diseases; (5) There are patients with transient arrhythmias caused by hematological system diseases, hyperthyroidism, electrolyte imbalance or reversible factors such as drugs; (6) There are patients with a recent surgical history of less than 2 months, or those with bleeding tendencies; (7) There are women in the pregnancy, lactation or preconception period; (8) There are patients who are allergic to or have an allergic constitution to the test drug; (9) There are patients currently participating in other clinical trials of drugs.

Design outcomes

Primary

MeasureTime frame
Dynamic electrocardiogram;Traditional Chinese Medicine Syndrome Score Scale;

Secondary

MeasureTime frame
Vascular endothelial growth factor;Hypoxia-inducible factor 1-alpha;

Countries

China

Contacts

Public ContactGong YUJin

Wuxi Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine China

ws1104147817@163.com18362047289

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Jun 11, 2026