Rheumatoid Arthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Aged 18 to 75 years; 2) Meeting the 2010 ACR/EULAR classification criteria for rheumatoid arthritis and the 2019 AWGS diagnostic criteria for sarcopenia; 3) DAS28 score < 5.1; 4) Not participating in regular physical exercise during leisure time; 5) Patient and family members consent and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1) Concurrent conditions including ankylosing spondylitis, systemic lupus erythematosus, gout, Sjögren's syndrome, and other rheumatic and immunological disorders; 2) Concurrent severe primary diseases affecting the cardiovascular, hepatic, renal, endocrine, or haematopoietic systems, or psychiatric disorders; 3) Concurrent severe RA complications such as secondary severe infections, vasculitis, and other acute or chronic infections; 4) Muscle atrophy resulting from primary muscular disorders (e.g., myasthenia gravis, muscular dystrophy), chronic debilitating conditions (e.g., malignant tumours), trauma, or other causes; 5) Inability to complete the trial due to severe disability, loss of self-care capacity, cognitive impairment, or similar factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Health Lifestyle Questionnaire - Disability Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| morning stiffness duration;Tender joint count;Swollen joint count;Visual Analog Scale (VAS);Disease Activity Score;Simplified Disease Activity Index;Clinical Disease Activity Index;TCM Syndrome Score;Grip strength;Body composition;6-Meter Gait Speed Test;Timed Up and Go Test;Anxiety Self-Rating Scale;Depression Self-Rating Scale; | — |
Countries
China
Contacts
Beijing University of Chinese Medicine