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Clinical Study on the Cerebral Mechanisms of Acupuncture for Knee Osteoarthritis

Clinical Study on the Cerebral Mechanisms of Acupuncture for Knee Osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001093
Enrollment
Unknown
Registered
2026-04-28
Start date
2026-03-02
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Acupuncture group:Acupuncture
Sham acupuncture group:Sham acupuncture

Sponsors

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: (1) Meeting the clinical diagnostic criteria for knee osteoarthritis (KOA); (2) Age = 50 years; (3) Knee pain duration = 3 months; (4) Kellgren-Lawrence (K-L) grade II or III within the past year; (5) Numerical Rating Scale (NRS) score = 4 within the past week; (6) Right-handedness.

Exclusion criteria

Exclusion criteria: Exclusion Criteria: (1) History of arthroscopic treatment within the past year, intra-articular injection within the past 6 months, history of knee arthroplasty, planned knee surgery, or knee pain attributable to other causes; (2) Presence of severe organic diseases, psychiatric or neurological disorders, or coagulation dysfunction; (3) Contraindications to magnetic resonance imaging (MRI) (e.g., claustrophobia, metallic implants); (4) History of acupuncture treatment within the past month; (5) Participation in other clinical trials within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Scale;

Secondary

MeasureTime frame
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC);12-Item Short Form Health Survey (SF-12);TCM Syndrome Score;Knee joint range of motion;

Countries

China

Contacts

Public ContactYuelong Cao

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

yuelongcao@shutcm.edu.cn13801927646

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Jun 11, 2026