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A randomized clinical controlled trial on the effect of Tai Chi exercise on cognitive function improvement in heart failure patients

Study on the effect of Tai Chi exercise on improving cognitive function in patients with chronic heart failure

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001058
Enrollment
Unknown
Registered
2026-04-24
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heart failure

Interventions

Tai Chi intervention group:Teaching and training intervention of eight style Tai Chi for 12 weeks (twice a week, for 1 hour each time)
Cognitive enhancement Tai Chi intervention group:The intervention method for the first 4 weeks is consistent with that of the Tai Chi intervention group, and cognitive enhancement content is added fro
control group:Conventional treatment methods such as aerobic exercise and medication therapy

Sponsors

Liaocheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 75 years old; 2. Meet the diagnostic criteria for heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) in the 2023 European Society of Cardiology (ESC) Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure; 3. The New York Heart Association (NYHA) classifies heart function as Grade II and III; 4. Understand the clinical trial project and voluntary participation, and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: · 1. Limited range of limb movement; 2. Uncontrolled hypertension (systolic blood pressure = 180mmHg or diastolic blood pressure = 100mmHg); 3. Resting heart rate exceeding 120 beats per minute, or accompanied by severe arrhythmia (ventricular fibrillation, ventricular tachycardia, etc.); 4. Patients with severe infections, chronic obstructive pulmonary disease, respiratory failure, or pulmonary heart disease; 5. Patients with other serious underlying diseases (including tumors and hematopoietic system diseases); 6. Serious mental illness or cognitive impairment; 7. Complicated with severe metabolic and hormonal disorders (such as hyperthyroidism and diabetes ketosis); 8. Life threatening comorbidities with an expected lifespan of less than 1 year; 9. Physical, visual, and auditory impairments that may hinder cognitive assessment; 10. Language disorders that may hinder cognitive assessment, such as severe articulation disorders or aphasia; 11. Patients enrolled in other clinical trials or rehabilitation interventions

Design outcomes

Primary

MeasureTime frame
Cognitive function;

Secondary

MeasureTime frame
Serum total cholesterol;Serum triglyceride;Serum high-density lipoprotein cholesterol;Serum low-density lipoprotein cholesterol;Blood glucose;Plasma brain natriuretic peptide;Plasma N-terminal brain natriuretic peptide;Plasma C-reactive protein;Plasma homocysteine;Serum uric acid;Serum troponin;Serum soluble growth-stimulating expression gene 2 protein;Cardiac ultrasound examination;Six-minute walking distance measurement;Measurement of quality of life;

Countries

China

Contacts

Public ContactQi Xuewen

Liaocheng People's Hospital

lhfq@163.com13306359016

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: May 1, 2026