heart failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 75 years old; 2. Meet the diagnostic criteria for heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) in the 2023 European Society of Cardiology (ESC) Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure; 3. The New York Heart Association (NYHA) classifies heart function as Grade II and III; 4. Understand the clinical trial project and voluntary participation, and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: · 1. Limited range of limb movement; 2. Uncontrolled hypertension (systolic blood pressure = 180mmHg or diastolic blood pressure = 100mmHg); 3. Resting heart rate exceeding 120 beats per minute, or accompanied by severe arrhythmia (ventricular fibrillation, ventricular tachycardia, etc.); 4. Patients with severe infections, chronic obstructive pulmonary disease, respiratory failure, or pulmonary heart disease; 5. Patients with other serious underlying diseases (including tumors and hematopoietic system diseases); 6. Serious mental illness or cognitive impairment; 7. Complicated with severe metabolic and hormonal disorders (such as hyperthyroidism and diabetes ketosis); 8. Life threatening comorbidities with an expected lifespan of less than 1 year; 9. Physical, visual, and auditory impairments that may hinder cognitive assessment; 10. Language disorders that may hinder cognitive assessment, such as severe articulation disorders or aphasia; 11. Patients enrolled in other clinical trials or rehabilitation interventions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum total cholesterol;Serum triglyceride;Serum high-density lipoprotein cholesterol;Serum low-density lipoprotein cholesterol;Blood glucose;Plasma brain natriuretic peptide;Plasma N-terminal brain natriuretic peptide;Plasma C-reactive protein;Plasma homocysteine;Serum uric acid;Serum troponin;Serum soluble growth-stimulating expression gene 2 protein;Cardiac ultrasound examination;Six-minute walking distance measurement;Measurement of quality of life; | — |
Countries
China
Contacts
Liaocheng People's Hospital