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Polyvinyl Alcohol Eye Drops Combined with Acupuncture for Dry Eye Disease: A Prospective Randomized Controlled Trial

The Clinical Efficacy of Polyvinyl Alcohol Eye Drops Combined with Acupuncture in the Treatment of Dry Eye Syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026001055
Enrollment
Unknown
Registered
2026-04-24
Start date
2025-07-01
Completion date
Unknown
Last updated
2026-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

Basic Treatment Group:Health education and counseling without medical intervention.
Polyvinyl alcohol treatment group:Using polyvinyl alcohol eye drops for treating dry eye syndrome patients.
Acupuncture Treatment Group:Using acupuncture to treat dry eye syndrome patients.
Polyvinyl alcohol combined with acupuncture treatment group:Using acupuncture plus polyvinyl alcohol eye drops for the treatment of dry eye patients.

Sponsors

Zhongxiang City People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria for dry eye syndrome: OSDI score =13 points, BUT =5 seconds (average of 3 measurements), Schirmer I test =5 mm/5 minutes (without topical anesthesia), corneal fluorescein staining =5 punctate staining points; (2) Age 18–70 years, gender unrestricted; (3) Disease duration =3 months; (4) Have not received systemic dry eye treatment in the past month; (5) Voluntarily participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Coexistence of other active ocular surface diseases; (2) A history of ocular surgery within the past 6 months; (3) Autoimmune diseases such as Sjögren's syndrome; (4) Severe dysfunction of heart, liver, or kidneys, or malignant tumors; (5) Pregnancy or lactation; (6) Allergy to polyvinyl alcohol; (7) A history of needle syncope or severe fear of acupuncture; (8) Participation in other clinical trials within the past month; (9) Use of medications that may affect tear secretion.

Design outcomes

Primary

MeasureTime frame
Tear Film Break-Up Time;

Secondary

MeasureTime frame
Ocular Surface Symptom Scoring;Corneal Fluorescein Staining;Serum and tear inflammatory factors;

Countries

China

Contacts

Public ContactHuang Rui

Zhongxiang City People's Hospital

1432279119@qq.com15927953057

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: May 1, 2026