Dyslipidemia in the Elderly
Conditions
Interventions
Experimental Group:Atorvastatin Calcium Tablets
Control Group:Atorvastatin Calcium Tablets + Yiqi Huoxue Formula
Sponsors
The Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Aged =60 and 3.4 mmol/L but <4.9 mmol/L); 3) Meet the TCM diagnostic criteria for dyslipidemia differentiated as Qi deficiency and blood stasis pattern; 4) No use of lipid-lowering agents, or have discontinued such medications for at least 2 weeks; 5) Liver function (AST, ALT) and renal function (Cr, UA) within normal ranges; 6) Willing to sign informed consent and able to actively participate.
Exclusion criteria
Exclusion criteria: 1) Dyslipidemia secondary to medications (e.g., antipsychotics, immunosuppressants, glucocorticoids, etc.); 2) TG =5.65 mmol/L, with risk of inducing serious complications such as acute pancreatitis, or when statin monotherapy fails to achieve effective lipid-lowering effects; 3) Hyperlipidemia secondary to other diseases such as nephrotic syndrome, hypothyroidism, or gout; 4) Dyslipidemia caused by adverse drug reactions, e.g., use of phenothiazines, heparin, or other medications that affect lipid metabolism; 5) Complicated by other severe conditions (e.g., acute exacerbation of severe cerebrovascular disease, cardiopulmonary system disease, or hematologic system disease); 6) Allergic constitution or a history of allergic reactions to the study medications; 7) Incomplete data provision or other factors that may interfere with the assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Low-Density Lipoprotein Cholesterol (LDL-C); | — |
Secondary
| Measure | Time frame |
|---|---|
| Total Cholesterol(TC);Triglyceride(TG);High-Density Lipoprotein Cholesterol(HDL-C); | — |
Countries
China
Contacts
Public ContactYang Xiaoping
The Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed