Acute exacerbation of chronic obstructive pulmonary disease, AECOPD
Conditions
Interventions
experimental group:Standard treatment of Western medicine and Qingre Huatan Decoction granules
COPD stable control group:None
Sponsors
The First Affiliated Hospital of Henan University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: AECOPD patients: (1) AECOPD patients who meet the diagnostic criteria of Western medicine; (2) Age = 40 years old, = 80 years old; (3) TCM syndrome differentiation is consistent with phlegm heat obstructing lung syndrome; (4) Did not participate in clinical studies of other drugs within 1 month before enrollment; (5) Voluntarily accept the study and sign the informed consent. Patients with stable COPD: (1) Patients with stable COPD who meet the diagnostic criteria of Western medicine; (2) Age = 40 years old, = 80 years old; (3) Voluntarily accept the study and sign the informed consent. Healthy person: (1) Age = 40 years old, = 80 years old; (2) Voluntarily accept the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Pregnant and lactating women; (2) Those who are not able to communicate normally, such as patients with unconsciousness, dementia and various mental disorders; (3) Patients with grade IV cardiac function, severe arrhythmia and hemodynamic instability; (4) Complicated with bronchiectasis, active pulmonary tuberculosis, pneumothorax, pleural effusion, pulmonary embolism and respiratory distress Neuromuscular diseases of motor function; (5) Combined tumor; (6) Patients treated outside the hospital for more than 7 days; (7) Respiratory failure requiring invasive mechanical ventilation; (8) Severe liver and kidney disease (severe liver disease refers to liver cirrhosis, portal hypertension and varicose veins Bleeding, severe kidney disease including aspiration and kidney transplantation); (9) Long term bedridden for various reasons; (10) Known allergic to therapeutic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| COPD assessment test questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| the treatment failure rate;symptom scores;the length of hospital stay;intubation rate;modified Medical Research Council; | — |
Countries
China
Contacts
Public ContactZhang Hailong
The First Affiliated Hospital of Henan University of Chinese Medicine
Outcome results
None listed