Early gastric cancer
Conditions
Interventions
Health control group:no intervention measures
Gastric precancerous lesion group:no intervention measures
Gastric cancer group:no intervention measures
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Gastric precancerous lesion group 1) Possess a gastroscopy pathology report within one year, indicating a diagnosis of chronic atrophic gastritis (with or without intestinal metaplasia), or gastric intraepithelial neoplasia; 2) Aged =18 and =75 years old, with no gender restrictions; 3) Agree to participate in this study and sign the informed consent form. (2) Gastric cancer group Possess a gastroscopy pathology report within one year, indicating early-stage gastric cancer or advanced gastric cancer (primary gastric cancer); 2) Aged =18 and =75 years old, with no gender restrictions; 3) Agree to participate in this study and sign the informed consent form. (3) Healthy group Possess a gastroscopy pathology report within the past year, which clearly states that the patient has no gastric mucosal-related lesions (including no atrophy, intestinal metaplasia, intraepithelial neoplasia, or carcinogenesis); 2) Aged =18 and =75 years old, with no gender restriction; 3) Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with severe primary diseases involving important systems such as the heart, brain, liver, lungs, kidneys, blood, and endocrine 2) Women who are currently in pregnancy or lactation, or who have recently been preparing for pregnancy 3) Those who are currently participating in or will participate in other drug clinical trials within 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area Under the Receiver Operating Characteristic Curve (AUC) of the early-stage gastric cancer grading diagnostic prediction model; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pepsinogen I;Pepsinogen II;Gastrin-17;Blood HP Antibody;Alpha-fetoprotein;Tumor Markers CEA;Tumor Markers CA19-9;Tumor Markers CA24-2;Traditional Chinese Medicine Constitution;gastrointestinal symptoms;tongue manifestation in traditional Chinese medicine;pulse condition in traditional Chinese medicine;facial diagnosis in traditional Chinese medicine;Anxiety and depression;somatization symptoms;quality of life;sex;age;Body Mass Index;Smoking and drinking habits;dietary habits;bowel movements;exercise status;sleep condition;HP infection status;Allergy history;Stomach surgery condition;Family history related to gastrointestinal tract; | — |
Countries
China
Contacts
Public ContactShengquan Fang
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed