Subthreshold depression
Conditions
Interventions
Low-frequency group: Treated once weekly
High-frequency group:Treated three times weekly.
Sponsors
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for subthreshold depression;(2) Subjects are aged between 18 and 60 years, with no gender restriction;(3) Score on the 17-item Hamilton Depression Scale (HAMD-17): 7 = HAMD-17 score < 17;(4) No prior antidepressant medication, and no acupuncture treatment for depression in the past 3 months;(5) Able to actively cooperate with the treatment and provide written informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with clinically diagnosed depression, previous mental illness, or organic mental disorders;(2) Patients with severe hepatic or renal dysfunction, severe arrhythmia, or cardiac insufficiency;(3) Pregnant or lactating women;(4) Depressive episodes induced by psychoactive substances or non-addictive substances;(5) Patients with suicidal ideation or suicidal behavior;(6) Patients intolerant to acupuncture treatment;(7) Patients with communication barriers or who are uncooperative with the study;(8) Other conditions judged by the investigator to be unsuitable for inclusion in the observation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale,HAMD 17; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale,HAMD 17;Hamilton Anxiety Rating Scale,HAMA-14; Self-rating Depression Scale;Self-Rating Anxiety Scale ;36-Item Short-Form Health Survey;Time-Resolved Lipidomics; | — |
Countries
China
Contacts
Public ContactXian Jin
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed