Patellofemoral Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Meeting the diagnostic criteria, being informed of the trial requirements and precautions, and having signed the informed consent form; 2) Aged between 40 and 75 years (inclusive); 3) A pain score of =4 during provocation (assessed using a 0–10 Numerical Rating Scale); 4) Presence of relevant symptoms for most of the time in the past month, with a relatively stable condition, and no prior pharmacological or other treatments for knee osteoarthritis (KOA) or patellofemoral osteoarthritis (PFOA) received. 5) Imaging examination indicating lateral patellofemoral joint osteophytes of grade =1.
Exclusion criteria
Exclusion criteria: 1) Knee pain primarily originating from other knee structures, or patients with significant referred pain due to concomitant hip or lumbar spine pathologies, or those with severe cardiovascular, hepatic, or renal impairments, rather than isolated PFOA; 2) Having undergone systematic physical therapy or similar manual therapy interventions for knee pain within the past 12 months; 3) Presence of contraindications to manual therapy, such as local skin lesions, severe infection, acute trauma, or inability to tolerate manual treatment; 4) Presence of psychiatric or intellectual disorders preventing cooperation with questionnaire surveys; 5) Pregnant or lactating women, or women with a pregnancy plan within the past six months; 6) Having received intra-articular knee injection therapy within the past 3 months; 7) Patients who have undergone patellofemoral joint arthroplasty; 8) Body Mass Index (BMI) = 35 kg/m²; 9) Concomitant moderate-to-severe tibiofemoral osteoarthritis, defined as a Kellgren–Lawrence grade = 3 on anteroposterior radiographs; 10) Radiographic evidence of significant joint deformity or severe articular cartilage destruction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pressure pain threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numerical rating scale;Quadriceps muscle strength;Modified 30-second sit-to-stand test; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Henan University of Traditional Chinese Medicine