Advanced Maternal Age Infertility
Conditions
Interventions
Intervention Group:Zishen Yutai Pill
Control group:Placebo
Sponsors
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
35 Years to 44 Years
Inclusion criteria
Inclusion criteria: (1) Age between 35 and 44 years old (inclusive of 35, exclusive of 44); (2) History of = 2 embryo transfer cycles, planning for FET; (3) At least one transferable cleavage-stage embryo or blastocyst available.
Exclusion criteria
Exclusion criteria: (1) Body Mass Index (BMI) = 28 kg/m2; (2) History of recurrent miscarriage (= 2 times); (3) Congenital malformation of reproductive organs or acquired organic lesions; (4) Untreated hydrosalpinx, endometrial polyps, or intrauterine adhesions; (5) Chromosomal structural or numerical abnormalities, or a history of genetic diseases; (6) Use of other traditional Chinese medicine or steroidal hormones within the past three months; (7) Concomitant severe heart, liver, kidney disease, or other systemic diseases; (8) Allergy to any component of the study medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Live Birth Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive Pregnancy;Embryo Implantation Rate;Clinical Pregnancy;Pregnancy Loss Rate;Pregnancy-induced hypertension;Gestational diabetes mellitus;Postpartum hemorrhage;Preterm birth rate (<37 gestational weeks at delivery);Neonatal birth weight;Incidence of Low Birth Weight Infants;Incidence of Small for Gestational Age (SGA);Macrosomia incidence;Large-for-gestational-age (LGA) incidence;NICU admission rate;Incidence of congenital anomalies;Neonatal mortality; | — |
Countries
China
Contacts
Public ContactSun Zhen-Gao
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed