chikungunya fever
Conditions
Interventions
experimental group:Experimental group: On the basis of the observation group, patients were treated with heat-sensitive moxibustion (administered on the day of enrollment). Fever phase (Treatment prin
Recovery period (treatment principle: interior syndrome of the three yin meridians, mainly nourishing qi and supporting vital qi) Acupoint selection: Danchong and Shenque
Each acupoint is probed and located, and moxibustion is applied with temperature control. The sensation of qi arrival is recorded, with two moxa cones per acupoint for about 40 minutes Take the medici
2) Operating environment: Keep the room quiet, and the temperature in the consultation room should be maintained at 20?-30?
3) Operational position: Depending on the patient's comfort level, choose lateral or prone position to fully expose the chest and abdominal areas for moxibustion application
4) Operation method and judgment criteria: First, perform sensory exploration and positioning. Use a lit mugwort stick to apply mild moxibustion at the "Danzhong and Shenque" areas on the patient's ch
Sponsors
Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Patients with common type of chikungunya fever; 2) Aged between 18 and 70 (inclusive); 3) From the time of nucleic acid positivity to enrollment within 72 hours. The informed consent process complies with regulations, and the informed consent form has been signed.
Exclusion criteria
Exclusion criteria: Subjects who meet any of the following criteria shall not be enrolled: 1) Those who have conjunctivitis, herpangina, suppurative tonsillitis, influenza, and other respiratory infectious diseases before screening or enrollment; 2) Patients who, according to the researchers' judgment, may have a high risk of rapidly progressing to severe disease; or those who have been diagnosed with severe chikungunya fever at screening (including severe bleeding; shock; severe organ damage such as ARDS or respiratory failure, acute myocarditis or acute heart failure, and acute liver injury (ALT and/or AST >1000) IU/L), acute renal insufficiency, encephalopathy or encephalitis, etc.); 3) The patient has used traditional Chinese medicine (including traditional Chinese patent medicines and simple preparations), antiviral drugs, antipyretic drugs, and external treatment methods of traditional Chinese medicine such as moxibustion and gua sha within 72 hours before enrollment; 4) History of epilepsy or febrile seizures; 5) Patients with severe malnutrition and those who also suffer from severe primary diseases of the heart, brain, liver, kidney, and hematopoietic systems, tumors, HIV infection, and autoimmune diseases; 6) Patients who require inpatient surgery within 7 days prior to enrollment; 7) Intolerance, allergy, or predisposition to allergies to the experimental medication or heat-sensitive moxibustion method. 8) Subjects who have used other trial medications within 30 days prior to baseline visit, or plan to use them during the study period; 9) The subject participates in other clinical studies within 30 days of the screening period; 10) Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of clinical symptom resolution (days);Time for fever to subside; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine test,;wo aspects of liver function;two renal function tests;C-reactive protein;Gut microbiota analysis;disease recurrence rate; | — |
Countries
China
Contacts
Public ContactTian Ning
Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed