Lumbar Disc Herniation (LDH)
Conditions
Interventions
Fixed PEEP Group:with a PEEP of 5
Individualized PEEP Group:Individualized PEEP Titrated by Dynamic Compliance (Cdyn)
Electroacupuncture Combined with Individualized PEEP Group:Electroacupuncture Combined with Cdyn-Titrated Individualized PEEP
Sponsors
Gansu Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) American Society of Anesthesiologists (ASA) Physical Status Classification II–III; 2) Elderly patients (aged 60–80 years) scheduled for endoscopic spinal surgery under general anesthesia, with an estimated operative time =2 hours; 3) Understand the study content and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria 1) History of contraindications to PEEP application, such as pneumothorax, pulmonary bullae, or severe emphysema. 2) Pre-existing respiratory or pulmonary diseases (e.g., asthma, chronic bronchitis, chronic obstructive pulmonary disease). 3) Presence of a cardiac pacemaker/defibrillator, or unstable cardiac conditions (e.g., recent myocardial infarction, severe heart failure). 4) Coagulation disorders, or local skin lesions/infections at the electroacupuncture sites (hands or feet). 5) Preoperative hemodynamic instability (e.g., shock) or severe hypoxemia. 6) Long-term use of analgesics or history of alcohol abuse. Elimination criteria 1) Those who voluntarily request to withdraw from the study during the trial; 2) Those who develop serious complications during or after surgery that affect the study; 3) Those who are lost to follow-up, making it impossible to collect outcome measures; 4) Operative time >4 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Soluble Receptor for Advanced Glycation End Products (sRAGE); Pulmonary Surfactant ;Clara Cell Secretory Protein (CC16);interleukin-6;interleukin-8;tumor necrosis factor-alpha; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation Index (OI);Respiratory Mechanics Parameters;Incidence of Postoperative Pulmonary Complications (PPCs);lung ultrasound score;intraoperative vasoactive agent use; | — |
Countries
China
Contacts
Public ContactWangChunai
Gansu Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed