Angina
Conditions
Interventions
Acupuncture group:Select bilateral Neiguan (PC-6) and Tongli (HT-5) acupoints and apply acupuncture therapy. Use the Park simulated needle device (Parksham device, PSD) combined with filiform needles,
Sham Acupuncture Group:Select bilateral Neiguan and Tongli acupoints and use sham acupuncture therapy. Use PSD combined with a retractable blunt needle
when the blunt needle contacts the skin, it retracts into the handle without penetrating the skin, without performing needle manipulation, and without achieving deqi, with a retention time of 30 minut
Healthy Control Group:not undergo acupuncture treatment.
Sponsors
Chongqing Changshou District Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for stable coronary artery disease as outlined in the "Guidelines for the Diagnosis and Treatment of Stable Coronary Artery Disease"; 2. Meets the CCS (Canadian Cardiovascular Society) grading criteria for angina severity, Grade I or II; 3. Age between 45 and 65 years (inclusive); 4. Disease duration of at least 3 months, with angina episodes occurring at least twice per week in the past month; 5. At least 2 months of history of standard basic drug therapy prior to enrollment (maintaining the same drugs, dosage, and administration); 6. Good compliance, willing to cooperate with the study, and patient has signed the informed consent form; 7. Right-handed.
Exclusion criteria
Exclusion criteria: 1. Pregnant and breastfeeding women, and those with plans to conceive within the next six months; 2. Individuals with severe primary diseases of the cardiovascular, digestive, urinary, respiratory, hematological, neurological, or endocrine systems that are not effectively controlled clinically; 3. Those who have progressed to acute coronary syndrome or severe arrhythmias; 4. Individuals with severe mental illness or intellectual disabilities who are unable to cooperate with questionnaire surveys; 5. Those with uncontrolled hypertension or diabetes; 6. Individuals who have undergone acupuncture treatment for cardiovascular diseases within the past month; 7. Those with a tendency to bleed or skin diseases; 8. Individuals currently participating in other clinical trials; 9. Conditions contraindicating MRI, such as the presence of metal implants or claustrophobia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of angina pectoris episodes;Functional Magnetic Resonance Imaging (fMRI); | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analog Scale score;Canadian Cardiovascular Society Angina Grading Criteria grading;Seattle Angina Questionnaire;Anxiety Self-Rating Scale;Depression Self-Rating Scale;Transcriptome sequencing;Metabolomics analysis; | — |
Countries
China
Contacts
Public Contactchen lin
Chongqing Changshou District Traditional Chinese Medicine Hospital
Outcome results
None listed