Post-cerebral infarction aphasia
Conditions
Interventions
Treatment group:Yi sui and Xing shen acupuncture + Language rehabilitation + Internal medicine basic treatment
Control Group:Non-meridian, non-acupoint acupuncture + Language rehabilitation + Internal medicine basic treatment
Healthy control group:None
Sponsors
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients: 1) Diagnosed with cerebral infarction according to Western medicine, with a disease duration of =6 months, aged 35–80 years; 2) Native Chinese speaker, right-handed; 3) Exhibits clear aphasic syndrome caused by the current cerebral infarction, confirmed as aphasia using the Chinese Rehabilitation Research Center Aphasia Examination (CRRCAE); 4) Educational level of elementary school or higher, with no other cognitive impairments; 5) Signed informed consent. Inclusion criteria for healthy controls: 1) Signed informed consent; 2) Aged 35–80 years; 3) No speech or language disorders; 4) No history of mental or neurological diseases or family history thereof; 5) Right-handed; 6) Able to cooperate with a 20-minute MRI scan.
Exclusion criteria
Exclusion criteria: Patient Exclusion Criteria: 1) Severe dysarthria, hearing impairment, cognitive impairment, or other reasons that prevent the patient from cooperating with the scale assessment; 2) Language disorders caused by impaired consciousness or general intellectual decline; 3) Language dysfunction caused by learning difficulties due to congenital or childhood diseases; 4) Damage to important organ functions (e.g., heart, liver, kidneys) that the investigator deems unsuitable for participation in this study; 5) Currently undergoing transcranial direct current stimulation (tDCS) therapy or taking medications such as piracetam, donepezil, memantine, bromocriptine, or galantamine, and unable to discontinue such therapy after enrollment; 6) Presence of contraindications for magnetic resonance imaging (MRI). Healthy Participant Exclusion Criteria: 1) Does not meet any of the inclusion criteria for healthy participants; 2) Presence of speech or language disorders; 3) History of mental or neurological diseases or family history thereof; 4) Non-right-handed individuals; 5) Unable to cooperate with a 20-minute MRI scan; 6) Currently undergoing transcranial direct current stimulation (tDCS) therapy or taking medications such as piracetam, donepezil, memantine, bromocriptine, or galantamine that may affect the central nervous system; 7) Damage to important organ functions (e.g., heart, liver, kidneys) that the investigator deems unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese Rehabilitation Research Center Aphasia Examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Multimodal magnetic resonance scanning;Stroke and Aphasia Quality of Life Scale-39; | — |
Countries
China
Contacts
Public ContactLü Tianli
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Outcome results
None listed