Corneal Epithelial Dysfunction
Conditions
Interventions
Control Group:Conventional topical eye drops were administered, including preservative-free artificial tears and autologous serum eye drops, along with tobramycin-dexamethasone ointment applied at bed
Observation group:In addition to the control group treatment, participants received oral administration of the modified Chu Feng Yi Sun Decoction. The formula consisted of Angelicae Sinensis Radix (Da
Sponsors
Bozhou Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Meeting the diagnostic criteria for CED; 2) CED graded as moderate or higher; 3) No restrictions on gender or age; 4) Participants are informed about the study and provide consent.
Exclusion criteria
Exclusion criteria: 1) CED complicated by corneal ulcer; 2) Presence of severe eyelid disorders, such as advanced meibomian gland dysfunction; 3) Coexisting immune system diseases, e.g., Sjögren's syndrome; 4) Severe cardiovascular or cerebrovascular diseases, abnormal liver or kidney function, or psychiatric disorders; 5) Other circumstances deemed by the research team as unsuitable for participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| best corrected visual acuity;ocular surface disease index;corneal fluorescein sodium staining; | — |
Secondary
| Measure | Time frame |
|---|---|
| breaking up time;corneal thickness; | — |
Countries
China
Contacts
Public ContactWang Longlong
Bozhou Hospital of Traditional Chinese Medicine
Outcome results
None listed