Sarcopenia
Conditions
Interventions
Case group (Sarcopenia group):Observational study with no intervention. Only standardized questionnaire surveys, body composition measurements, and biological sample collection will be conducted.
Control group (Non-sarcopenic group):Observational study with no intervention. Only standardized questionnaire surveys, body composition measurements, and biological sample collection will be conducte
Sponsors
Wangjing Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Case group: Meet the diagnostic criteria for sarcopenia; Control group: Non-sarcopenic individuals during the same period; (2) Age = 50 years, no gender restrictions; (3) Basic self-care ability in activities of daily living, and capable of independently cooperating to complete the required walking and physical performance tests; (4) Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Individuals with an implanted cardiac pacemaker, or coexisting severe/uncontrolled cardiovascular diseases, wasting diseases (e.g., malignancies), or active infectious diseases; (2) Patients with Alzheimer's disease, psychiatric disorders, or other cognitive/mental impairments who are unable to cooperate with the survey and physical tests; (3) Long-term use of oral corticosteroids, muscle relaxants, or other medications known to affect muscle metabolism; (4) Currently participating in other interventional clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Appendicular skeletal muscle mass index;handgrip strength;Traditional Chinese Medicine diagnostic information and syndrome elements; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight;Body mass index;Fat mass;Body fat percentage;Waist-to-hip ratio;Short Physical Performance Battery score;Timed Up and Go test time;Tinetti Performance Oriented Mobility Assessment score;FRAIL scale score;Activities of Daily Living score;Geriatric Depression Scale score;Mini Nutritional Assessment Short-Form score;Pittsburgh Sleep Quality Index score;Serum biomarkers related to muscle metabolism;Bone mineral density; | — |
Countries
China
Contacts
Public ContactLi Linghui
Wangjing Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed