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Investigating the Neural Mechanisms of Baduanjin Intervention for Major Depressive Disorder Using Multimodal Neuroimaging and Artificial Intelligence

Investigating the Neural Mechanisms of Baduanjin Intervention for Major Depressive Disorder Using Multimodal Neuroimaging and Artificial Intelligence

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000910
Enrollment
Unknown
Registered
2026-04-09
Start date
2026-05-06
Completion date
Unknown
Last updated
2026-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major depressive disorder

Interventions

Baduanjin exercise group :Participants underwent the 2018 version of the Baduanjin exercise program promoted by the General Administration of Sport of China for 10 weeks under researchers' guidance. T

Sponsors

The Rehabilitation Hospital affiliated to Fujian University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Aged 18 to 65 years, regardless of gender; Diagnosed with major depressive disorder (MDD) according to the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5); Score ranging from 8 to 23 on the 17-item Hamilton Rating Scale for Depression (HRSD-17); Score > 20 on the Montreal Cognitive Assessment (MoCA); Voluntarily agree to participate in the study and sign the written informed consent form; Right-handed.

Exclusion criteria

Exclusion criteria: Comorbid with organic diseases or other mental disorders, including but not limited to schizophrenia; Taking any medications that affect cerebral activity; Pregnant or lactating; With alcoholism or substance dependence; Patients with suicidal or violent aggressive tendencies; Having contraindications to MRI scans.

Design outcomes

Primary

MeasureTime frame
HRSD17;

Secondary

MeasureTime frame
Gray Matter Volume;resting state functional connectivity;

Countries

China

Contacts

Public ContactJiajia Ye

The Rehabilitation Hospital affiliated to Fujian University of Traditional Chinese Medicine

328699151@qq.com13950472365

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: May 1, 2026