Unstable angina pectoris
Conditions
Interventions
Standard Western medicine treatment group:Western Standard Treatment
Qijin Dan group:Qijindan treatment in addition to standard Western medical therapy
Sponsors
Wuxi Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) A documented history of myocardial infarction, or coronary artery stenosis of = 50% confirmed via coronary angiography (CAG) or coronary computed tomography angiography (CCTA); with a concurrent Traditional Chinese Medicine (TCM) differentiation of Intermingled Phlegm and Blood Stasis Syndrome. (2) Stable vital signs and a sound general physical condition. (3) Aged between 18 and 80 years. (4) Voluntary provision of written informed consent prior to study enrollment.
Exclusion criteria
Exclusion criteria: (1) Patients diagnosed with other acute or severe cardiovascular conditions (e.g., severe arrhythmias, structural heart diseases), or concurrent acute systemic diseases including acute cerebral infarction and severe pulmonary insufficiency. (2) Patients presenting with severe heart failure, malignant tumors, or severe primary dysfunctions of the pulmonary, hepatic, renal, hematopoietic, or endocrine systems; as well as those with active gastrointestinal bleeding, gastric ulcers, or a bleeding diathesis that would preclude completion of the trial. (3) Patients with psychiatric disorders, severe cognitive impairment, or legally defined disabilities that prevent adequate informed consent or protocol adherence. (4) Women who are pregnant, lactating, or planning to conceive; or individuals with a known hypersensitivity to any components of the investigational drug. (5) Patients who are currently participating in, or have participated in, another clinical trial within the preceding three months. (6) Patients who refuse participation or are unwilling to comply with the study procedures. Patients meeting any one of the aforementioned criteria will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor Protein p53;Growth differentiation factor15;Vascular endothelial growth factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment efficacy of angina symptoms;Electrocardiogram efficacy;Seattle Angina Questionnaire (SAQ);Efficacy on TCM syndromes;Efficacy on blood stasis syndrome;Blood lipid levels; | — |
Countries
China
Contacts
Public ContactShi Man
Wuxi Traditional Chinese Medicine Hospital
Outcome results
None listed