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Efficacy of Tai Chi Training Combined with Transcranial Alternating Current Stimulation (tACS) for Improving Mild Cognitive Impairment in the Elderly and Analysis of Electroencephalogram (EEG) Spectral Features

Efficacy of Tai Chi Training Combined with Transcranial Alternating Current Stimulation (tACS) for Improving Mild Cognitive Impairment in the Elderly and Analysis of Electroencephalogram (EEG) Spectral Features

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000886
Enrollment
Unknown
Registered
2026-04-03
Start date
2026-05-06
Completion date
Unknown
Last updated
2026-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep Disorders and Cognitive Impairments

Interventions

Control Group:tACS sham stimulation and Tai Chi Chuan
Experimental Group:tACS real stimulation and tai chi

Sponsors

Suzhou City Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Age 60-75 years; (2) Meets the diagnostic criteria for primary insomnia as per the third edition of the International Classification of Sleep Disorders; (3) Pittsburgh Sleep Quality Index (PSQI) score >5 points before treatment; (4) Montreal Cognitive Assessment (MoCA) score <26 points; (5) Without comorbid mental disorders such as depression and anxiety, or neurological diseases such as stroke, dementia, Parkinson's disease, or chronic pain; (6) Have not engaged in regular physical exercise for the past three months (at least 3 times per week, each session lasting at least 20 minutes); (7) Right-handed; (8) Able to understand and cooperate, voluntarily participate, and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Short Geriatric Depression Scale (GDS-15) score = 9 points; (2) History of taking any antipsychotic medication within the past month; (3) Uncontrolled hypertension (systolic blood pressure > 180 mmHg or diastolic blood pressure 11%); (5) Unable to cooperate with Tai Chi training or tACS protocols, such as those with motor dysfunction caused by neurological diseases, musculoskeletal system diseases, severe organ diseases, or other contraindications for exercise; (6) Presence of metal substances implanted in the brain; (7) Unable to complete outcome assessments, such as severe aphasia, sensory impairments, or illiteracy; (8) Currently participating in other research studies that may affect the results of this study.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment;Pittsburgh Sleep Quality Index Scale;

Secondary

MeasureTime frame
Quantitative EEG;Polysomnography;Insomnia Severity Index;Activities of Daily Living Assessment Scale;Hamilton Depression Rating Scale;Hamilton Anxiety Rating Scale;

Countries

China

Contacts

Public ContactQian Wenjun

Suzhou Municipal Hospital

Qwenjun005@163.com130 6381 0224

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: May 1, 2026