Gastrointestinal adverse reactions caused by azithromycin
Conditions
Interventions
treatment group:Treatment Group: Acupressure Therapy: After disinfecting the Zhongwan, Zusanli, and Neiguan acupoints with 75% alcohol, the operator wears sterile gloves and uses disposable sterile ac
Blank Control Group:Intervention with blank press-tack needle acupressure: After routine disinfection of Zhongwan (CV12), Zusanli (ST36), and Neiguan (PC6) acupoints with 75% alcohol, the operator wor
Sponsors
Putuo Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
3 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Children meeting the diagnostic criteria for Mycoplasma pneumoniae pneumonia; 2. Aged 3-14 years with clear description of gastrointestinal symptoms (nausea, abdominal pain, vomiting, diarrhea); 3. Completed a 3-day course of oral or intravenous azithromycin; 4. No history of azithromycin or traditional Chinese medicine allergies; 5. Absence of gastrointestinal reactions, digestive system disorders, or acute abdominal conditions; 6. Informed consent from both the child and legal guardian, with signed consent documents
Exclusion criteria
Exclusion criteria: 1. Patients with gastric perforation, pyloric obstruction, severe dysplasia of gastric mucosa, suspected malignant transformation; 2. Patients with hepatic and renal insufficiency, heart failure, cerebrovascular accident, severe infection, malignant tumor; 3. Patients with hypersensitivity to the acupuncture needle used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary efficacy indicators: TCM syndrome scores for abdominal pain, vomiting, and abdominal distension.; | — |
Secondary
| Measure | Time frame |
|---|---|
| (2) Secondary efficacy indicators: Individual syndrome scores (anorexia, nausea, loose stools, constipation, excessive flatus); | — |
Countries
China
Contacts
Public ContactFangjuLiao
Putuo Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed