Indolent Lymphoma
Conditions
Interventions
Treatment group:Differential Diagnosis and Treatment Based on Typology
Sponsors
The First Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: I. Age range: 18 - 80 years old, gender not restricted. Before inclusion, informed consent must be signed; II. According to the NCCN 2024 guidelines, the diagnosis through histopathology is clear: chronic lymphocytic leukemia / small B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and patients who can undergo observation and waiting; III. There are measurable and assessable lesions for efficacy evaluation, and the expected survival period is more than 4 months.
Exclusion criteria
Exclusion criteria: I. Pregnant or lactating women, or those planning pregnancy during treatment or unable to take effective contraceptive measures; II. Severe immunodeficiency, or active infection, or coexisting other autoimmune diseases such as SLE, RA, etc.; III. Uncontrolled hypertension or diabetes; IV. Significantly abnormal liver or kidney function; V. Positive serum HIV or HCV test results, or HBV in active stage; VI. Patients with poor compliance; VII. Any other situation that the researcher deems inappropriate for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival;Cytokine;Lymphocyte subsets;Genetic fragment variation;Hotspot gene mutations;Chromosome karyotype; | — |
Countries
China
Contacts
Public ContactBaodong Ye
The First Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed