Knee Osteoarthritis
Conditions
Interventions
the Mongolian Medicine Sand Therapy Group :Mongolian medicine sand therapy combined with magnetic therapy and Mongolian herbal bath intervention
Conventional Drug Group:Oral medication combined with topical patches
Sponsors
thics Review Committee, Inner Mongolia Autonomous Region Institute of Mongolian and Chinese Medicine
Eligibility
Sex/Gender
All
Age
55 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Kellgren-Lawrence grade II–III. (2) TCM syndrome differentiation: "excessive Badagan Heyi syndrome". (3) Visual Analogue Scale (VAS) score = 4, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score = 30.
Exclusion criteria
Exclusion criteria: (1) Complicated with other severe joint diseases, such as rheumatoid arthritis, gouty arthritis, etc. (2) Suffering from severe diseases of vital organs such as heart, liver and kidney, or mental illness that makes the patient unable to cooperate with treatment and testing. (3) Having used drugs affecting metabolism or inflammatory indicators within the past 1 month, such as glucocorticoids, immunosuppressants, intra-articular injection therapy, etc. (4) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS);Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC);Serum Differential Metabolites;Differentially expressed metabolites in Synovial Fluid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Tumor Necrosis Factor-a(TNF-a);Serum Interleukin-1ß(IL-1ß);Serum Matrix Metalloproteinase-3 (MMP-3); | — |
Countries
China
Contacts
Public ContactJiyaDu
Inner Mongolia Autonomous Region Institute of Mongolian and Chinese Medicine
Outcome results
None listed