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Study on the Regulatory Effect of Electroacupuncture on Intraocular Pressure in Primary Open-Angle Glaucoma Patients

Study on the Regulatory Effect of Electroacupuncture on Intraocular Pressure in Primary Open-Angle Glaucoma Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000835
Enrollment
Unknown
Registered
2026-03-31
Start date
2026-04-07
Completion date
Unknown
Last updated
2026-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Open-Angle Glaucoma (POAG)

Interventions

Electroacupuncture Group:Electroacupuncture
Sham electroacupuncture group:Sham Electroacupuncture

Sponsors

Shanghai University of Traditional Chinese Medicine Affiliated Yueyang Integrated Chinese and Western Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Diagnosed with mild/moderate POAG in one/both eyes (Hodapp-Parrish-Anderson criteria) =3 months; Age =18 and =65 years, any gender; Stable use of prostaglandin analogs (PGA), carbonic anhydrase inhibitors (CAI), ß-adrenergic blockers, a2-adrenergic agonists, Rho kinase inhibitors (monotherapy or dual therapy) =1 month before enrollment; IOP =18 mmHg and =25 mmHg; Anterior chamber angle Shaffer grade =2; Central corneal thickness (CCT) 480-600 µm in study eye; Voluntary informed consent and compliance with trial procedures. Note: Hodapp-Parrish-Anderson criteria: Mild (mean deviation (MD) > -6 dB), Moderate (MD -12 to -6 dB), Severe (MD < -12 dB).

Exclusion criteria

Exclusion criteria: Participation in other oral/topical trials or use of non-protocol IOP-affecting medications (e.g., corticosteroids, antihypertensives) within 1 month; Ophthalmic laser/surgical treatment =6 months before enrollment; Active intraocular inflammation/infection; Best Corrected Visual Acuity (BCVA) <20/40; Vision-affecting ocular pathologies (e.g., cataract, moderate/severe diabetic retinopathy); Corneal abnormalities (scarring, dystrophy); Electroacupuncture contraindications: a) Inability to complete treatment (pacemaker/implantable device, epilepsy), b) Coagulation disorders/thrombocytopenia/anticoagulant use (warfarin, rivaroxaban); Pregnancy/lactation/pregnancy planning.

Design outcomes

Primary

MeasureTime frame
Absolute IOP Reduction;—

Secondary

MeasureTime frame
Absolute IOP;Proportion of Study Eyes with =20% IOP Reduction;Proportion of Study Eyes with IOP =18 mmHg/=15 mmHg;IOP Range (Max-Min);IOP Standard Deviation;Visual Evoked Potential;Pattern Electroretinogram;Contrast Sensitivity;Glaucoma Symptom Scale Score;Glaucoma Quality of Life-15 Questionnaire Score;Mean Deviation in Visual Field;Best corrected visual acuity;Optical Coherence Tomography RNFL/GCC;—

Countries

China

Contacts

Public ContactMa Xiaopeng

Shanghai Research Institute of Acupuncture and Meridian

pengpengma@163.com13917140446

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: May 1, 2026