Amnestic mild cognitive impairment
Conditions
Interventions
Electroacupuncture group:Buyuan Yizhi Granules (composed of ginseng, ginger-processed pinellia tuber, etc.
administered continuously for 8 weeks, once every other day, 4 days per week) plus finger exercises (10–15 minutes before and after each herbal treatment, 4 times per week, 32 sessions in total over 8
Waiting Treatment Group:During the observation period, only finger exercise training was performed 4 times per week (synchronized with the treatment group), 10–15 minutes each time. Upon completion of
Sponsors
Affiliated Hospital of Shaanxi University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Meet the Western medical diagnostic criteria for mild cognitive impairment and the traditional Chinese medical diagnostic criteria for the marrow insufficiency and phlegm-turbidity pattern; 2.Aged 40 to 80 years old (inclusive), with no gender restriction; 3.Right-handed, free of visual and auditory impairments, and able to cooperate with scale assessments; 4. No participation in other clinical trials in the past 3 months, no long-term use of specific medications before enrollment, or completion of the washout period; 5. Voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Presence of organic diseases that could explain cognitive impairment; 2.Presence of alarm symptoms or long-term use of non-steroidal anti-inflammatory drugs; 3.Cognitive impairment caused by identifiable specific etiologies; 4.Complicated with severe aphasia or neurological deficits, unable to cooperate with cognitive assessments; 5.Diagnosis of other types of dementia; 6.History of alcoholism, drug abuse, or psychotropic substance abuse; 7.History of acupuncture allergy or severe coagulation dysfunction (for the waiting-list control group); 8.Hypersensitivity to any herbal ingredient in Buyuan Yizhi Granules (such as ginseng, salvia miltiorrhiza, pinellia, etc.) (for the treatment group)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alzheimer's Disease Assessment Scale - Cognitive Subscale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment Scale;Mini-Mental State Examination (MMSE) Scale Score;Activities of Daily Living Scale Scoring;Pittsburgh Sleep Quality Index Scale; | — |
Countries
China
Contacts
Public ContactDiwu Yongchang
Shaanxi University of Chinese Medicine
Outcome results
None listed