Anal fistula
Conditions
Interventions
Experimental Group:Skin-contracting powder medication change method
Control Group:Iodophor dressing change
Sponsors
Nanjing City Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Must meet the diagnostic criteria for high-complexity anal fistula; (2) Age between 18 and 60 years old, with no gender restrictions; (3) Preoperative auxiliary examination results will not impact the treatment of this disease; (4) Establish an intravenous line before surgery; (5) Be informed about the study content, sign the informed consent form, and be willing to accept long-term follow-up after surgery.
Exclusion criteria
Exclusion criteria: (1) Patients with hematological disorders or diseases of the heart, brain, or kidneys; those who have recently taken immunosuppressants or anticoagulants; (2) Patients with organic conditions such as tumors or inflammatory bowel disease; (3) Patients with anal fistulas caused by systemic infections such as hematological or tuberculosis-related infections; (4) Patients who are pregnant or breastfeeding; (5) Patients with allergies to relevant medications, those with allergic constitutions, or those with a tendency to develop keloids; (6) Patients with mental disorders or those who have taken psychotropic medications in the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor Necrosis Factor alpha;Interleukin-6;Vascular Endothelial Growth Factor;Epidermal Growth Factor;Postoperative wound area;Wound Area Reduction Rate;Wound healing time;Hematoxylin and Eosin staining;Masson staining; | — |
Secondary
| Measure | Time frame |
|---|---|
| Granulation Morphology;Granulation Tissue Color Rating;Wound Exudate Scoring;Wound pain score;Anal Incontinence Assessment;Recurrence rate; | — |
Countries
China
Contacts
Public ContactKang Ding
Nanjing City Hospital of Traditional Chinese Medicine
Outcome results
None listed