Sarcopenic osteoporosis
Conditions
Interventions
Intervention Group:Remote Intervention Scheme for Traditional Chinese Medical Exercises under Intelligent Monitoring (Including Personalized Prescriptions, Smart Device Monitoring, Remote Video Guidan
Control Group:Routine health education and general activity recommendations, including the distribution of the "Sarcopenic Osteoporosis Home Care Manual," a monthly 15-minute telephone follow-up, with
Sponsors
Wuxi Ninth People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 65 to 80 years old; 2. Meet diagnostic criteria for sarcopenic osteoporosis: - Sarcopenia (AWGS 2019 criteria): Grip strength below the critical value (males <28 kg, females <18 kg) and 5-time sit-to-stand test duration =12 seconds; - Osteoporosis: Dual-energy X-ray absorptiometry (DXA) measurement, lumbar spine (L1-L4) or hip bone density T-score =-2.5; 3. Mini-Mental State Examination (MMSE) score =24 points, with basic cognitive ability; able to operate a smartphone or tablet computer; 4. Voluntarily participate and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from severe or unstable cardio-cerebrovascular, liver, or kidney diseases; 2. Having a history of fracture or orthopedic surgery in the past six months; 3. Suffering from rheumatoid arthritis, Parkinson's disease, or other neurological or autoimmune diseases that affect mobility; 4. Long-term use of drugs that affect bone metabolism or muscle (e.g., glucocorticoids, androgens, etc.); 5. Having contraindications for exercise or being deemed unsuitable for participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grip Strength (Maximum Grip Strength of Dominant Hand);Simple Physical Performance Test Total Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone Mineral Density (Lumbar Spine L1-L4);Berg Balance Scale Total Score;Timed Stand-Up and Walk Test Time;International Osteoporosis Foundation Quality of Life Questionnaire Total Score;Fall incidence;Serum myostatin level;Serum Osteocalcin Level Change Value;Serum Type I Procollagen N-terminal Propeptide (PINP) Level Change Value;Serum ß-carboxy-terminal collagen type I telopeptide (ß-CTX) level change value; | — |
Countries
China
Contacts
Public ContactZhou Zhiyi
The Ninth People's Hospital of Wuxi City
Outcome results
None listed