colorectal cancer
Conditions
Interventions
modified Si Jun Zi Decoction:Postoperative oral administration of Modified Si Jun Zi Decoction
Placebo:Postoperative oral administration of warm water
Sponsors
Jiading Hospital of Traditional Chinese medicine, Shanghai
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with colorectal cancer according to diagnostic criteria. 2. Patients scheduled for elective laparoscopic colon cancer resection or laparoscopic Dixon procedure for rectal cancer. 3. Patients aged between 40 and 80 years old. 4. Patients with normal preoperative examination of cardiovascular, pulmonary, hepatic, and renal functions. 5. Patients with no evidence of abdominal lymph node metastasis or distant metastasis to the liver, lungs, etc., as determined by preoperative and intraoperative examinations. 6. Patients who have been fully informed about their condition, willing to participate in this study, and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients undergoing abdominoperineal resection for rectal cancer (Miles procedure). 2. Patients with severe chronic diseases of the heart, lungs, liver, kidneys, brain, immune system, hematologic system, endocrine system, etc. 3. Patients where preoperative auxiliary examinations reveal widespread distant metastasis and extramural invasion, making complete resection impossible. 4. Patients who have undergone neoadjuvant therapy, radiotherapy, chemotherapy, or other treatments prior to surgery. 5. Patients with preoperative findings of moderate to severe anemia, or excessive intraoperative blood loss, or postoperative findings of moderate to severe anemia meeting transfusion criteria, requiring blood transfusion therapy. 6. Patients with severe malnutrition, or long-term use of immunosuppressive agents and corticosteroids. 7. Patients with poor compliance, who may arbitrarily discontinue or change treatment medications or methods during therapy. 8. Patients with mental illness or severe cognitive dysfunction. 9. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bowel sound recovery time;First Flatus;First Defecation;Postoperative ambulation;Drain Tube Removal Time;Hospital Stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood Routine Test;Liver and kidney function Test;Blood Cell Flow Cytometry;Serum gastrin;Serum Immunoglobulin;16S RNA sequencing; | — |
Countries
People's Republic of China
Contacts
Public ContactXiaowen Tang
Jiading Hospital of Traditional Chinese medicine, Shanghai
Outcome results
None listed